| Considering Functional Outcomes as Efficacy Endpoints in Pediatric Low-Grade Glioma Clinical Trials: An FDA Educational Symposium. Clinical cancer research : an official journal of the American Association for Cancer Research | J Fangusaro, RA Avery, MJ Fisher, RJ Packer, KS Walsh, A Schouten-van Meeteren, D Karres, D Bradford, V Bhatnagar, H Singh, PG Kluetz, M Donoghue, ES Duke | 06/03/2024 |
| Towards Consistency in Pediatric Brain Tumor Measurements: Challenges, Solutions, and the Role of AI-Based Segmentation. Neuro-oncology | AM Familiar, A Fathi Kazerooni, A Vossough, JB Ware, S Bagheri, N Khalili, H Anderson, D Haldar, PB Storm, AC Resnick, BH Kann, M Aboian, C Kline, M Weller, RY Huang, SM Chang, JR Fangusaro, LM Hoffman, S Mueller, M Prados, A Nabavizadeh | 05/21/2024 |
| Resistance, rebound, and recurrence regrowth patterns in pediatric low-grade glioma treated by MAPK inhibition: A modified Delphi approach to build international consensus-based definitions-International Pediatric Low-Grade Glioma Coalition. Neuro-oncology | P O'Hare, T Cooney, P de Blank, DH Gutmann, M Kieran, T Milde, J Fangusaro, M Fisher, S Avula, R Packer, K f*ckuoka, K Mankad, S Mueller, AJ Waanders, E Opocher, E Bouffet, E Raabe, NE Werle, AA Azizi, NJ Robison, P Hernáiz Driever, M Russo, N Schouten, CM van Tilburg, A Sehested, J Grill, P Bandopadhayay, JP Kilday, O Witt, DM Ashley, BB Ertl-Wagner, U Tabori, DR Hargrave | 05/14/2024 |
| Consensus framework for conducting phase I/II clinical trials for children, adolescents, and young adults with pediatric low-grade glioma: Guidelines established by the International Pediatric Low-Grade Glioma Coalition Clinical Trial Working Group. Neuro-oncology | S Mueller, J Fangusaro, AO Thomas, TS Jacques, P Bandopadhayay, P de Blank, RJ Packer, M Fouladi, AS van Meeteren, D Jones, A Perry, Y Nakano, D Hargrave, D Riedl, NJ Robison, M Partanen, MJ Fisher, O Witt | 03/04/2024 |
| Indoximod-based chemo-immunotherapy for pediatric brain tumors: A first-in-children phase I trial. Neuro-oncology | TS Johnson, TJ MacDonald, R Pacholczyk, D Aguilera, A Al-Basheer, M Bajaj, P Bandopadhayay, Z Berrong, E Bouffet, RC Castellino, K Dorris, BR Eaton, N Esiashvili, JR Fangusaro, N Foreman, D Fridlyand, C Giller, IM Heger, C Huang, N Kadom, EP Kennedy, N Manoharan, W Martin, C McDonough, RS Parker, V Ramaswamy, E Ring, A Rojiani, RF Sadek, S Satpathy, M Schniederjan, A Smith, C Smith, BE Thomas, R Vaizer, KK Yeo, MK Bhasin, DH Munn | 02/02/2024 |
| Primary Diffuse Leptomeningeal Melanomatosis in a Child with Extracranial Metastasis: Case Report. Current oncology (Toronto, Ont.) | SW Shahab, P Patil, JR Fangusaro, B Patteson, A Goldman-Yassen, BR Eaton, W Boydston, M Schniederjan, D Aguilera | 01/20/2024 |
| Pediatric low-grade glioma: State-of-the-art and ongoing challenges. Neuro-oncology | J Fangusaro, DT Jones, RJ Packer, DH Gutmann, T Milde, O Witt, S Mueller, MJ Fisher, JR Hansford, U Tabori, D Hargrave, P Bandopadhayay | 01/05/2024 |
| Phase I trial of panobinostat in children with diffuse intrinsic pontine glioma: A report from the Pediatric Brain Tumor Consortium (PBTC-047). Neuro-oncology | M Monje, T Cooney, J Glod, J Huang, CJ Peer, D Faury, P Baxter, K Kramer, A Lenzen, NJ Robison, L Kilburn, A Vinitsky, WD Figg, N Jabado, M Fouladi, J Fangusaro, A Onar-Thomas, IJ Dunkel, KE Warren | 12/08/2023 |
| Optimizing preclinical pediatric low-grade glioma models for meaningful clinical translation. Neuro-oncology | T Milde, J Fangusaro, MJ Fisher, C Hawkins, FJ Rodriguez, U Tabori, O Witt, Y Zhu, DH Gutmann | 11/02/2023 |
| Children's Oncology Group's 2023 blueprint for research: Central nervous system tumors. Pediatric blood & cancer | SES Leary, A Onar-Thomas, J Fangusaro, NG Gottardo, K Cohen, A Smith, A Huang, D Haas-Kogan, M Fouladi | 09/01/2023 |
| Evaluating Focal Areas of Signal Intensity (FASI) in Children with Neurofibromatosis Type-1 (NF1) Treated with Selumetinib on Pediatric Brain Tumor Consortium (PBTC)-029B. Cancers | N Pillay-Smiley, J Leach, A Lane, T Hummel, J Fangusaro, P de Blank | 03/31/2023 |
| The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science. Neoplasia (New York, N.Y.) | JV Lilly, JL Rokita, JL Mason, T Patton, S Stefankiewiz, D Higgins, G Trooskin, CA Larouci, K Arya, E Appert, AP Heath, Y Zhu, MA Brown, B Zhang, BK Farrow, S Robins, AM Morgan, TQ Nguyen, E Frenkel, K Lehmann, E Drake, C Sullivan, A Plisiewicz, N Coleman, L Patterson, M Koptyra, Z Helili, N Van Kuren, N Young, MC Kim, C Friedman, A Lubneuski, C Blackden, M Williams, V Baubet, L Tauhid, J Galanaugh, K Boucher, H Ijaz, KA Cole, N Choudhari, M Santi, RW Moulder, J Waller, W Rife, SJ Diskin, M Mateos, DW Parsons, IF Pollack, S Goldman, S Leary, C Caporalini, AM Buccoliero, M Scagnet, D Haussler, D Hanson, R Firestein, J Cain, JJ Phillips, N Gupta, S Mueller, G Grant, M Monje-Deisseroth, S Partap, JP Greenfield, R Hashizume, A Smith, S Zhu, JM Johnston, JR Fangusaro, M Miller, MD Wood, S Gardner, CL Carter, LM Prolo, J Pisapia, K Pehlivan, A Franson, T Niazi, J Rubin, M Abdelbaki, DS Ziegler, HB Lindsay, AG Stucklin, N Gerber, OM Vaske, C Quinsey, BR Rood, J Nazarian, E Raabe, EM Jackson, S Stapleton, RM Lober, DE Kram, C Koschmann, PB Storm, RR Lulla, M Prados, AC Resnick, AJ Waanders | 01/01/2023 |
| Paediatric Strategy Forum for medicinal product development in mitogen-activated protein kinase pathway inhibitors: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration. European journal of cancer (Oxford, England : 1990) | AD Pearson, C Allen, J Fangusaro, C Hutter, O Witt, S Weiner, G Reaman, M Russo, P Bandopadhayay, S Ahsan, A Barone, E Barry, T de Rojas, M Fisher, E Fox, JG Bender, L Gore, D Hargrave, D Hawkins, B Kreider, AJ Langseth, G Lesa, F Ligas, M Marotti, LV Marshall, K Nasri, K Norga, K Nysom, A Pappo, G Rossato, N Scobie, M Smith, E Stieglitz, B Weigel, A Weinstein, R Viana, D Karres, G Vassal | 12/01/2022 |
| MEK inhibitors for neurofibromatosis type 1 manifestations: Clinical evidence and consensus. Neuro-oncology | PMK de Blank, AM Gross, S Akshintala, JO Blakeley, G Bollag, A Cannon, E Dombi, J Fangusaro, BD Gelb, D Hargrave, A Kim, LJ Klesse, M Loh, S Martin, C Moertel, R Packer, JM Payne, KA Rauen, JJ Rios, N Robison, EK Schorry, K Shannon, DA Stevenson, E Stieglitz, NJ Ullrich, KS Walsh, BD Weiss, PL Wolters, K Yohay, ME Yohe, BC Widemann, MJ Fisher | 11/02/2022 |
| Pattern of treatment failures in patients with central nervous system non-germinomatous germ cell tumors (CNS-NGGCT): A pooled analysis of clinical trials. Neuro-oncology | A Fonseca, C Faure-Conter, MJ Murray, J Fangusaro, S Bailey, S Goldman, S Khatua, D Frappaz, G Calaminus, G Dhall, JC Nicholson, E Bouffet, U Bartels | 11/02/2022 |
| Nervous system (NS) Tumors in Cancer Predisposition Syndromes. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics | P Patil, BB Pencheva, VM Patil, J Fangusaro | 10/01/2022 |
| Clinical Activity of Mitogen-Activated Protein Kinase-Targeted Therapies in Patients With Non-V600 BRAF-Mutant Tumors. JCO precision oncology | M Dankner, Y Wang, R Fazelzad, B Johnson, CA Nebhan, I Dagogo-Jack, NJ Myall, G Richtig, JWP Bracht, M Gerlinger, E Shinozaki, T Yoshino, D Kotani, JR Fangusaro, O Gautschi, J Mazieres, JA Sosman, S Kopetz, V Subbiah, MA Davies, AL Groover, RJ Sullivan, KT Flaherty, DB Johnson, A Benedetti, DW Cescon, A Spreafico, G Zogopoulos, AAN Rose | 08/01/2022 |
| Corrigendum to: LTBK-01. Updates On The Phase Ii And Re-treatment Study Of AZD6244 (Selumetinib) For Children With Recurrent Or Refractory Pediatric Low Grade Glioma: A Pediatric Brain Tumor Consortium (PBTC) Study. Neuro-oncology | JR Fangusaro, A Onar-Thomas, TY Poussaint, S Wu, AH Ligon, NI Lindeman, A Banerjee, R Packer, LB Kilburn, IF Pollack, IA Qaddoumi, PG Fisher, G Dhall, PA Baxter, SG Kreissman, LA Doyle, MA Smith, M Fouladi, IJ Dunkel | 08/01/2022 |
| Phase II trial of response-based radiation therapy for patients with localized germinoma: a Children's Oncology Group study. Neuro-oncology | U Bartels, A Onar-Thomas, SK Patel, D Shaw, J Fangusaro, G Dhall, M Souweidane, A Bhatia, L Embry, CL Trask, ES Murphy, S MacDonald, S Wu, JM Boyett, S Leary, M Fouladi, A Gajjar, S Khatua | 06/01/2022 |
| A Phase 2 Trial of Response-Based Radiation Therapy for Localized Central Nervous System Germ Cell Tumors: Patterns of Failure and Radiation Dosimetry for Nongerminomatous Germ Cell Tumors. International journal of radiation oncology, biology, physics | ES Murphy, G Dhall, J Fangusaro, U Bartels, M Fouladi, D Shaw, S Khatua, CW Hughes, A Panigraphy, M Ioakeim-Ioannidou, M Souweidane, D Morris, A Gajjar, S Wu, A Onar-Thomas, DA Haas-Kogan, SM MacDonald | 05/01/2022 |
| Imaging response assessment for CNS germ cell tumours: consensus recommendations from the European Society for Paediatric Oncology Brain Tumour Group and North American Children's Oncology Group. The Lancet. Oncology | G Morana, D Shaw, SM MacDonald, C Alapetite, T Ajithkumar, A Bhatia, H Brisse, C Jaimes, T Czech, G Dhall, J Fangusaro, C Faure-Conter, M Fouladi, D Hargrave, JH Harreld, D Mitra, JC Nicholson, M Souweidane, B Timmermann, G Calaminus, U Bartels, B Bison, MJ Murray | 05/01/2022 |
| Comprehensive Genomic Profiling of High-Risk Pediatric Cancer Patients Has a Measurable Impact on Clinical Care. JCO precision oncology | RJ Summers, SM Castellino, CC Porter, TJ MacDonald, GD Basu, S Szelinger, MK Bhasin, T Cash, AB Carter, RC Castellino, JR Fangusaro, SG Mitchell, MG Pauly, B Pencheva, DS Wechsler, DK Graham, KC Goldsmith | 04/01/2022 |
| Multicenter Analysis of Genomically Targeted Single Patient Use Requests for Pediatric Neoplasms. Journal of clinical oncology : official journal of the American Society of Clinical Oncology | HS Sabnis, DS Shulman, B Mizukawa, N Bouvier, A Zehir, J Fangusaro, VA Fabrizio, C Whitlow, M Winchester, L Agresta, B Turpin, DS Wechsler, SG DuBois, J Glade-Bender, SM Castellino, N Shukla | 12/01/2021 |
| A phase II trial of selumetinib in children with recurrent optic pathway and hypothalamic low-grade glioma without NF1: a Pediatric Brain Tumor Consortium study. Neuro-oncology | J Fangusaro, A Onar-Thomas, TY Poussaint, S Wu, AH Ligon, N Lindeman, O Campagne, A Banerjee, S Gururangan, LB Kilburn, S Goldman, I Qaddoumi, P Baxter, G Vezina, C Bregman, Z Patay, JY Jones, CF Stewart, MJ Fisher, LA Doyle, M Smith, IJ Dunkel, M Fouladi | 10/01/2021 |
| Clinical Pharmaco*kinetics and Pharmacodynamics of Selumetinib. Clinical pharmaco*kinetics | O Campagne, KK Yeo, J Fangusaro, CF Stewart | 03/01/2021 |
| Neonatal Central Nervous System Tumors. Clinics in perinatology | S Shahab, J Fangusaro | 03/01/2021 |
| Advances in the classification and treatment of pediatric brain tumors. Current opinion in pediatrics | J Fangusaro, P Bandopadhayay | 02/01/2021 |
| Phase 1 study of pomalidomide in children with recurrent, refractory, and progressive central nervous system tumors: A Pediatric Brain Tumor Consortium trial. Pediatric blood & cancer | J Fangusaro, DA Mitchell, M Kocak, GW Robinson, PA Baxter, EI Hwang, J Huang, A Onar-Thomas, IJ Dunkel, M Fouladi, KE Warren | 02/01/2021 |
| Phase 2 Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors. Frontiers in oncology | J Fangusaro, MG Cefalo, ML Garré, LV Marshall, M Massimino, B Benettaib, N Biserna, J Poon, J Quan, E Conlin, J Lewandowski, M Simco*ck, N Jeste, DR Hargrave, F Doz, KE Warren | 01/01/2021 |
| Implications of new understandings of gliomas in children and adults with NF1: report of a consensus conference. Neuro-oncology | RJ Packer, A Iavarone, DTW Jones, JO Blakeley, E Bouffet, MJ Fisher, E Hwang, C Hawkins, L Kilburn, T MacDonald, SM Pfister, B Rood, FJ Rodriguez, U Tabori, V Ramaswamy, Y Zhu, J Fangusaro, SA Johnston, DH Gutmann | 06/09/2020 |
| Pineoblastoma in children less than six years of age: The Head Start I, II, and III experience. Pediatric blood & cancer | MS Abdelbaki, MH Abu-Arja, TB Davidson, JR Fangusaro, JR Stanek, IJ Dunkel, G Dhall, SL Gardner, JL Finlay | 06/01/2020 |
| Response assessment in paediatric low-grade glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group. The Lancet. Oncology | J Fangusaro, O Witt, P Hernáiz Driever, AK Bag, P de Blank, N Kadom, L Kilburn, RM Lober, NJ Robison, MJ Fisher, RJ Packer, T Young Poussaint, L Papusha, S Avula, AA Brandes, E Bouffet, D Bowers, A Artemov, M Chintagumpala, D Zurakowski, M van den Bent, B Bison, KW Yeom, W Taal, KE Warren | 06/01/2020 |
| The "Risk" in Pediatric Low-Grade Glioma. Cancer cell | J Fangusaro, P Bandopadhayay | 04/13/2020 |
| Pineoblastoma segregates into molecular sub-groups with distinct clinico-pathologic features: a Rare Brain Tumor Consortium registry study. Acta neuropathologica | BK Li, A Vasiljevic, C Dufour, F Yao, BLB Ho, M Lu, EI Hwang, S Gururangan, JR Hansford, M Fouladi, S Nobusawa, A Laquerriere, MB Delisle, J Fangusaro, F Forest, H Toledano, P Solano-Paez, S Leary, D Birks, LM Hoffman, A Szathmari, C Faure-Conter, X Fan, D Catchpoole, L Zhou, KAP Schultz, K Ichimura, G Gauchotte, N Jabado, C Jones, D Loussouarn, K Mokhtari, A Rousseau, DS Ziegler, S Tanaka, SL Pomeroy, A Gajjar, V Ramaswamy, C Hawkins, RG Grundy, DA Hill, E Bouffet, A Huang, A Jouvet | 02/01/2020 |
| Phase II Trial of Response-Based Radiation Therapy for Patients With Localized CNS Nongerminomatous Germ Cell Tumors: A Children's Oncology Group Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology | J Fangusaro, S Wu, S MacDonald, E Murphy, D Shaw, U Bartels, S Khatua, M Souweidane, HM Lu, D Morris, A Panigrahy, A Onar-Thomas, M Fouladi, A Gajjar, G Dhall | 12/01/2019 |
| Improved neuropsychological outcomes following proton therapy relative to X-ray therapy for pediatric brain tumor patients. Neuro-oncology | JP Gross, S Powell, F Zelko, W Hartsell, S Goldman, J Fangusaro, RR Lulla, NP Smiley, JH Chang, V Gondi | 07/11/2019 |
| A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor. Cancer cell | P Sin-Chan, I Mumal, T Suwal, B Ho, X Fan, I Singh, Y Du, M Lu, N Patel, J Torchia, D Popovski, M Fouladi, P Guilhamon, JR Hansford, S Leary, LM Hoffman, JM Mulcahy Levy, A Lassaletta, P Solano-Paez, E Rivas, A Reddy, GY Gillespie, N Gupta, TE Van Meter, H Nakamura, TT Wong, YS Ra, SK Kim, L Massimi, RG Grundy, J Fangusaro, D Johnston, J Chan, L Lafay-Cousin, EI Hwang, Y Wang, D Catchpoole, J Michaud, B Ellezam, R Ramanujachar, H Lindsay, MD Taylor, CE Hawkins, E Bouffet, N Jabado, SK Singh, CL Kleinman, D Barsyte-Lovejoy, XN Li, PB Dirks, CY Lin, SC Mack, JN Rich, A Huang | 07/08/2019 |
| Selumetinib in paediatric patients with BRAF-aberrant or neurofibromatosis type 1-associated recurrent, refractory, or progressive low-grade glioma: a multicentre, phase 2 trial. The Lancet. Oncology | J Fangusaro, A Onar-Thomas, T Young Poussaint, S Wu, AH Ligon, N Lindeman, A Banerjee, RJ Packer, LB Kilburn, S Goldman, IF Pollack, I Qaddoumi, RI Jakacki, PG Fisher, G Dhall, P Baxter, SG Kreissman, CF Stewart, DTW Jones, SM Pfister, G Vezina, JS Stern, A Panigrahy, Z Patay, B Tamrazi, JY Jones, SS Haque, DS Enterline, S Cha, MJ Fisher, LA Doyle, M Smith, IJ Dunkel, M Fouladi | 07/01/2019 |
| Transcriptional repressor REST drives lineage stage-specific chromatin compaction at Ptch1 and increases AKT activation in a mouse model of medulloblastoma. Science signaling | THW Dobson, RH Tao, J Swaminathan, S Maegawa, S Shaik, J Bravo-Alegria, A Sharma, B Kennis, Y Yang, K Callegari, AR Haltom, P Taylor, M Kogiso, L Qi, S Khatua, S Goldman, RR Lulla, J Fangusaro, TJ MacDonald, XN Li, C Hawkins, V Rajaram, V Gopalakrishnan | 01/22/2019 |
